Badrawy, Hosny and Ibrahim, Abeer (2013) JAK-2V617F Mutation in Acute Leukemia (South Egypt Experience). International Blood Research & Reviews, 2 (1). pp. 1-7. ISSN 23217219
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Abstract
Aim: To search for JAK2V617F mutation in patients with acute myeloid and acute lymphoblastic leukemia in south Egypt.
Study Design: JAK2V617F mutation detected by amplification refractory mutation system (ARMS) -PCR.
Place and Duration of Study: Department of clinical pathology and department of medical oncology, South Egypt Cancer Institute, Assiut University, Assiut, Egypt, between December 2010 and December 2012.
Method: We included 90 patients (58 men and 32 women; age range 2-67 years) with denovo acute leukemia (30 acute myeloid leukemia and 60 acute lymphoblastic leukemia), JAK-2 V617F mutation using ARMS-PCR was done for all the patients.
Results: JAK-2 V617F mutation was absent in all of the studied patients.
Conclusion: Our results confirm the finding published previously which reported that JAK2 V617F mutation is very rare or absent in acute leukemia.
Item Type: | Article |
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Subjects: | STM Digital Library > Medical Science |
Depositing User: | Unnamed user with email support@stmdigitallib.com |
Date Deposited: | 10 Jul 2023 05:15 |
Last Modified: | 18 May 2024 07:45 |
URI: | http://archive.scholarstm.com/id/eprint/1414 |